Rb suppresses collective invasion, circulation and metastasis of breast cancer cells in CD44-dependent manner.
Basal-like breast carcinomas (BLCs) present with extratumoral lymphovascular invasion, are highly metastatic, presumably through a hematogenous route, have augmented expression click here of CD44 oncoprotein and relatively low levels of retinoblastoma (Rb) tumor suppressor.However, the causal relation among these features is not clear.Here, we show